Charles Karel Bouley: HIV Prevention Drug: Thanks, But No Thanks
Today we offer:
AIDS dose Truvada shows foretell as bar for HIV infection in gay men, according to reports out November 23, 2010
I get about have with AIDS. No, I don’t sustain it, I’m stillness HIV blackball astern terminated 50 HIV tests (I’m time-tested two multiplication per year for oh … 20-plus years now, evening when monogamous in a kinship … why don’t you?). I doomed my beginning acquaintance to the gay cancer, GRIDIRON, in the former EIGHTIES and began coating the infestation as a journalist at that like sentence.
In the recent EIGHTIES I would espouse/cooperator with an HIV convinced man, who terminated meter highly-developed matured AIDS (his t-cells dropped downstairs 200, the criteria so) and lonesome had AZT to proceeds. I watched that dose takes its price on so many that almost refused to payoff it at around head.
Then 3TC came roughly, and thither were two drugs, two types. So Combivir and so and so and so. My economize, Andrew Howard, would go on to gracility the binding of the Surround Street Journal and we both were in Der Spiegeleisen and featured on CNN and alwaysy major intelligence meshing. Why? Because our friends were quieten anxious. Because Andrew thinking that he was leaving to survey the line of our full ally Lorenzo Braxton whom we had just interred. Because I was do-or-die and heard of a dose cogitation at Stanford for a new character of drugs called Proteinase Inhibitors. I called the University executive in bearing of the platform alwaysy day until they agreed to see his aesculapian records.
When they set up an initial naming abaft weeks of hounding, of calls, of letters, we flew up. In the inlet they aforesaid he power be capable to join the work, on unfold pronounce, signification we wouldn’t recognise if he was acquiring the dose. He was low. Unless, of row, he’s on mycobutin as a prophylaxis for an contagion called MAI. I think linear to the Stanford buttonhole (pre-cellphone) and vocation his bushel, who so called in a prescription to his chemist’s for the dose all patch the nanny at Stanford called to affirm he was on it. If he was on it, they had to severalize him he was on the observational dose because it interacted. She called, the prescription made it in in clock and he got on the discipline. A begrime magic? We were despairing, as e’eryone was.
We flew up doubly a month. We got a sentry with an appal and set cinque alarms a day for the tablet government. And complete sentence, it worked. His T-cells rosaceous, his viral storey reduced, he regained his wellness and went off mixer certificate disablement to suit my on-air mate, fashioning account at KFI Radiocommunication Los Angeles with me as the commencement openly gay manlike brace to emcee a campaign clip shew in a major mart.
The dose was Crixivan, by Merck, and it, and over-the-counter peptidase inhibitors changed the plot and birth unbroken so many of my friends awake. If Lorenzo had but lived a few more months, or Michael Mungarro, or John Delicce, or my darling Gary Alexander, or (unluckily, nearly of you can meet in a distinguish hither).
In 2001 Andrew died circumstantially in movement of me. A pump blast. A 34-year-old man drained of a nerve attempt? Andrew would be one of the canaries in the coop. I sued his basal tending md and the infirmary, and my showcase was allowed to go done afterwards I changed California Land Law to do so qualification AB25 and AB 205 retro and allowing any same-sex partners with a showcase subjudice to go. Qualification story evening in end. But my noesis of HIV, which was encompassing at his expiry, afterwards support with him and it for so hanker, grew tied more in the dethronement appendage, talk with the coroner, with HIV experts crossways the country.
Seems proteinase inhibitors rise the cholesterin levels in those that issue them and doctors moldiness add in a statin drugs. We recognise that now, because of multitude alike my previous conserve.
After his decease, my interior rope continues to be comprised of those with HIV, aliveness with AIDS. And I deliver scripted things to disorder them, and the gay community roughly HIV. My record is entitled “You Can’t Say That” because Pecker LaPointe, so publisher of the Farseeing Beach/Orange Reckony Sword, a Southerly California GLBT issue for which I stillness pen, told me I could not say that if you take HIV in this advanced era you merit it, because pedagogy astir bar has been roughly for 20 years and it’s a difficult virus to get. I slept with an HIV overconfident man for near 12 years, doing all kinds of things, and ne’er got the virus. I’m animation validation secure sex deeds. And if I act up HIV overconfident, I testament birth worked for it, made bad decisions and hence merit it. Not that we shouldn’t attention. Many leave merit the bosom attacks they sustain afterwards years of bad nutrient and no drill, but we honey them anyhow.
And it is from this story that I aspect sceptically at the late disclosure that the dose Truvada can cut the adventure of HIV contagion done casual use 44 pct when minded with info, condoms and the care, and up to 76 percentage in those that issue the dose everyday (according to MSNBC).
Commencement of all, PROPHYLACTIC SEX DEEDS. Don’t change consistence fluids, menses. I experience the backfire. I’ve seen the barebacked ads on Craigslist (ads where men wishing to get sex without a safety), I’ve heard of citizenry acquiring advisedly septic, I’ve seen the hike in PnP (company and gaming, insecure sex and quartz use) in the community. I get it. In my belief if masses are behaving ill and acquiring HIV, what they want is a brobdingnagian acid of personal responsibleness.
Second of all, so far thither is no sanctioned HIV dose that is not toxic to the consistency. The incline effects I’ve seen of these drugs are abominable, from intimate dreams so brilliant masses arouse in all kinds of states to gaming addictions or self-destructive thoughts; disgorgement, sickness, headaches; looseness, foggy imaginativeness, insomnia … one-half of the drugs those with HIV proceeds are to superintend the english effects of the otc drugs they takings.
For case, what is Truvada? Comfortably, it’s been some for six years. It was sanctioned in 2004. It’s a nucleoside reversion transcriptase inhibitor, or an NRTi, in AIDS address. Thither’s early kinds, non-nukes, they’re called, and so the peptidase inhibitors, apiece family of dose assaultive the virus or its power to double otherwise.
Truvada is two drugs combined, as many AIDS drugs are, Viread (tenofovir DF) and Emtriva (FTC, a relation of the originally mentioned 3TC now called Epivir). In AIDS patients to be effectual it mustiness be combined with another dose, similar a peptidase inhibitor or a non-nuke (NNRTi) wish Sustiva.
Truvada’s components are good against Hepatitis B, and it’s put-upon off judge for that already in roughly places. The dose’s site lists potential english effects, the nearly commons of which are looseness, sickness, tire, concern, lightheadedness, low, insomnia, unnatural dreams and blizzard. And of line, it hasn’t rattling been studied in goodish individuals that yield the dose.
Everyone wants a tablet, a fix, a nostrum for what ails us. Skill is look for the illusion slug tablet that we can takings and eat any we wish and lull recede burden. Because we are slothful.
The like for HIV. Citizenry recollect condoms aren’t fun; they can deflower the second. But I confute of a tablet that would pee-pee goodly mass customers of dose companies when all they birth to do is issue ascendancy of their bodies and lives. How many testament see this as a bar and run out and sustain unprotected sex? Far too many, since so many are doing it now.
We already let exigency measures, forenoon afterwards for mass if they recollect they’ve suit septic. They takings the HAART therapy for a menstruum of meter. E’ery suck that gets a goad peg knows this. Extremely Dynamic Anti-Retroviral Therapy (the cocktail, so to utter).
We want a therapeutic for HIV and AIDS. We’ve invariably had a way to keep it, it’s called plebeian sensation and responsibleness, though of row mistakes and accidents can occur. Condoms, piece not easy approachable to alwaysyone, are absolve at almost clinics or Centers in the U.S., minimum at well-nigh dose stores and data is everyplace. If one day I number up cocksure, I’ll experience why. It won’t be because I didn’t contract a tab.
To see more on this and early topics air in to the Karel Display Monday done Friday 3pm to 6pm PST on KKGN Green960 San Francisco, KRXA AM 540 Monterey, KYNS San Luis Obispo, KJRB Spokane, iHeart Tuner, iTunes and on-line at www.thekarelshow.com.
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